Personalised Brain Stimulation for Treatment of Obsessive-Compulsive Disorder

Grant number: 1138711 | Funding period: 2018 - 2021

Completed

Abstract

Obsessive-Compulsive Disorder (OCD) affects more than 230,000 Australians, 25% of whom attempt suicide. This project will use a novel method to profile people with OCD based on patterns of brain activity and symptoms, and assess if such profiling can improve the efficacy of brain stimulation interventions for OCD. Results from this study will provide evidence supporting the use of personalised brain stimulation as a viable therapy for OCD.

Related publications (6)

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Brain-Predicted Age Associates With Psychopathology Dimensions in Youths

VL Cropley, Y Tian, K Fernando, S Mansour L., C Pantelis, L Cocchi, A Zalesky

2021-04-01

Background: This study aimed to investigate whether dimensional constructs of psychopathology relate to variation in patterns of b..

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Neural Correlates of Sleep Recovery following Melatonin Treatment for Pediatric Concussion: A Randomized Controlled Trial

KK Iyer, A Zalesky, L Cocchi, KM Barlow

2020-12-15

Evidence-based treatments for children with persistent post-concussion symptoms (PPCS) are few and limited. Common PPCS complaints..

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Default mode network anatomy and function is linked to pediatric concussion recovery

KK Iyer, A Zalesky, KM Barlow, L Cocchi

2019-12-01

Objective: To determine whether anatomical and functional brain features relate to key persistent post–concussion symptoms (PPCS) ..

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Large-scale brain modes reorganize between infant sleep states and carry prognostic information for preterms

A Tokariev, JA Roberts, A Zalesky, X Zhao, S Vanhatalo, M Breakspear, L Cocchi

2019-12-01

Sleep architecture carries vital information about brain health across the lifespan. In particular, the ability to express distinc..

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A multivariate neuroimaging biomarker of individual outcome to transcranial magnetic stimulation in depression

RFH Cash, L Cocchi, R Anderson, A Rogachov, A Kucyi, AJ Barnett, A Zalesky, PB Fitzgerald

2019-11-01

The neurobiology of major depressive disorder (MDD) remains incompletely understood, and many individuals fail to respond to stand..

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Relating brain connectivity with persistent symptoms in pediatric concussion

KK Iyer, KM Barlow, B Brooks, Z Ofoghi, A Zalesky, L Cocchi

2019-05-01

Persistent post-concussion symptoms (PCS) in children following a mild traumatic brain injury (mTBI) are a growing public health c..

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